Eukaryotic messenger RNA and informosomes

Interference of nonsense mutations with eukaryotic messenger RNA stability.

The fine structure map of the yeast URA 3 gene was established by meiotic recombination, and amber nonsense mutations were located at different points on the map. The effect of the length of the labeling time on the specific radioactivity of ura 3 messenger RNA and on its repartition between poly(A)-RNA and RNA not containing poly(A) has been followed in nonsense mutants. Nonsense mutations red...

Translation of Eukaryotic Messenger Rna in Various Heterologous Systems

Translation of oncogenic viral RNA and eukaryotic messenger RNA in the E. coli cell-free system.

Mitochondrial protein synthesis: RNA with the properties of Eukaryotic messenger RNA.

A heterogeneous RNA fraction with properties resembling those of messenger RNA was identified in mammalian mitochondria. Synthesis of contaminating RNA of nuclear origin was suppressed by treatment with camptothecin. Labeling of the messenger-like RNA is completely inhibited by ethidium bromide, a specific inhibitor of mitochondrial functions.Although mitochondrial protein synthesis resembles t...

Messenger RNA.